Objective To investigate the regulation of stem cell-driven tissue renewal by canonical Wnt and TGFβ/bone morphogenetic protein (BMP) pathways in the native human colonic epithelium ... Real-time ...

The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

These factors impact several signaling pathways in chondrocytes, collectively regulating joint homeostasis. Some of these factors alleviate OA progression by playing positive roles in its pathogenesis ...

LOS ANGELES (KABC) -- New changes to a federal regulation are expected to make it easier for veterans to find housing. Veterans Affairs Secretary Denis McDonough and Los Angeles leaders said ...

Increased understanding of signal transduction mechanisms and gene regulation involved in immune responses has created opportunities for the discovery of novel therapeutic compounds useful in treating ...

University of Cambridge, United Kingdom; University of South Bohemia in České Budějovice, Czech Republic; ...

Keros believes that cibotercept has the potential to increase the signaling of bone morphogenic protein (“BMP”) pathways through this inhibition of activin A and activin B signaling ...

Keros believes that cibotercept has the potential to increase the signaling of bone morphogenic protein (“BMP”) pathways through this inhibition of activin A and activin B ...