Autophagy is a cellular degradation pathway for the clearance of damaged or superfluous proteins and organelles. The recycling of these intracellular constituents also serves as an alternative ...

As a crucial cellular process involved in degrading and recycling damaged organelles and proteins, autophagy-related (ATG) proteins mediated autophagy plays a significant role in various physiological ...

The array of quality control is guaranteed through distinct mechanisms that involve location, concentration, conformation, and the turnover of individual proteins, such as autophagy, proteasomal ...

The winner of the 32nd annual Martha's Vineyard All School Spelling Bee is fifth-grader Juliet Merrill from the Edgartown School and the winning word was jalapeño. On Friday, the middle school ...

This cover highlights the article Multimodal mechanisms of human centriole engagement and disengagement by Kei K. Ito, Shoji Hata, Daiju Kitagawa and colleagues. The cover image depicts the centriole ...

In auxotrophic tumors, the absence of arginine triggers autophagy and apoptosis in tumor cells, whereas normal cells can survive under similar conditions. Cancer cells can accumulate elevated levels ...

Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...

Background There is substantial interest in the cardiovascular effects of e-cigarette use, highlighting the need to update our knowledge on the subject. We conducted this review to analyse whether ...

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, China. (Y.E.L., S.L., Litao Wang, Y.D., L. Wu, H.C., T ...