An extensive molecular characterization of 150 human thoracic ... aortic pathology. Early intervention to enhance these mitochondrial processes could potentially slow disease progression ...

Real-time observation of certain biochemical processes in blood vessels from mice has revealed a previously unknown similarity between atherosclerosis, also known as vascular calcification ...

Vascular. 2010;18(1):41-44. As a consequence of the widespread availability of advanced diagnostic tests, thoracic aorta thrombi will continue to be diagnosed with increased frequency ...

1 Division of Cardiology, Cardiovascular and Thoracic Department, “Città della Salute e della Scienza” Hospital ... through direct effects on ion channel function and disrupted calcium handling, can ...

In this work the essential contribution of Piezo1 channels to arterial medial calcification is demonstrated. The presence of Piezo1 was proved on human aortic smooth muscle samples using ...

Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide ... and potential pitfalls of signal interferences and disruption and has been used in our ...

Figure. Matrix metalloproteinase (MMP) activation plays a central role in arterial proinflammatory remodeling and stiffening, which is a structural and functional signature of aging, hypertension, and ...

Usually the deficiency of a molecule leads to an overall increase, decrease, or no change in murine atherosclerotic lesion burden, but the distribution of lesions in the arterial tree remains ...