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We used single-walled carbon nanotube (CNT) films to modulate the morpho-functional and proliferative characteristics of astrocytes. When plated on the CNT films of various thicknesses, astrocytes ...
This paper discusses the regulatory role of reactive astrocytes in neuroinflammation and PD neurodegeneration, as well as the reduction of neuroinflammation and the progression of PD through exercise ...
Knocking out PERK in astrocytes reduces amyloid plaque burden in 5xFAD (top). The knockouts more quickly found the escape hole in the Barnes maze test (bottom). [Courtesy of Chen et al., Neuron, 2025.
免疫组化显示,gdnf+stz组的反应性微胶质细胞比例(iba1r%)与stz组无差异(p>0.05),均显著高于对照组,表明gdnf未能阻断stz诱导的神经炎症级联反应。 讨论部分指出,该研究首次证实AAV9介导的星形胶质细胞GDNF过表达可重塑细胞形态并部分保护认知功能,但其疗效受限于神经炎症的持续存在。
Astrocytes, once thought to be the brain’s housekeepers, may actually be silent powerhouses of memory. MIT scientists have proposed a bold new model where these star-shaped cells, with their intricate ...
By mimicking how astrocytes link various neurons together, future AI models might unlock more efficient memory storage. “While neuroscience initially inspired key ideas in AI, the last 50 years of ...
Abstract. Neuron–astrocyte associative memory. Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, ...
What’s more, these cells are everywhere. Estimates vary, but astrocytes may constitute about 20 percent of brain cells, says Kevin Guttenplan, a coauthor of one of the new studies and ...
The brain also contains billions of astrocytes — star-shaped cells with many long extensions that allow them to interact with millions of neurons. Although they have long been thought to be mainly ...