News

Sweden: A study published in the Journal of Clinical Investigation has revealed that red blood cells (RBCs) in individuals ...
Elevated Arginase Levels Contribute To Vascular Eye Disease Such As Diabetic Retinopathy Date: August 24, 2009 Source: Medical College of Georgia Summary: Elevated levels of the enzyme arginase ...
The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.
Their study has also revealed what the scientists believe is a key role for the enzyme arginase in causing asthmatic symptoms. The research, led by Marc E. Rothenberg, M.D., Ph.D., of Cincinnati ...
IO112 is the company’s fully-owned, novel investigational product candidate containing a single Arginase 1-derived peptide designed to engage and activate Arginase 1-specific human T cells.
Josh, who is 26, lives with rare and debilitating Arginase 1 Deficiency. "He's missing the arginase enzyme in his body to break down arginine. The arginine is toxic, it's a neurotoxin," said ...
For example, Arginase 1 (ARG1) secreted from cells downregulates receptors on immune cells to limit cell activation and proliferation in solid tumors. However, it is unclear which cells are the source ...
Aeglea BioTherapeutics has announced that their lead investigational therapy, pegzilarginase, has been granted Breakthrough Therapy designation for the treatment of arginase 1 deficiency (ARG1-D).
Many states test for arginase and citrin deficiencies. A handful also test for OTC and CPS1 deficiencies. Long-term treatment can manage UCD symptoms. Your child will need frequent blood tests ...
Daewoong Pharmaceutical Co. Ltd. has divulged arginase-1 (ARG1) inhibitors reported to be useful for the treatment of cancer.