The loss of cardiomyocytes in failing or cardiomyopathic hearts is gradual and not accompanied by inflammation or major histomorphologic deformity. Apoptosis, therefore, seems to be the most ...

The enzyme arginase-II has an important role in cardiac aging, and blocking it could help hearts stay young longer.

The interaction of PCMT1 with Mst1 was confirmed by co-immunoprecipitation in both co-transfected HEK-293 cells and native cardiomyocytes, in which PCMT1 interacted with the kinase domain of Mst1, but ...

In addition, Meis1, a TALE family homeodomain protein, was recently found to be critical in regulation of the cardiac growth switch from proliferation to hypertrophy. 219 Meis1 deletion in mouse ...

Type 1 DCM models were established utilizing C57BL/6 mice and primary neonatal mouse cardiomyocytes (NMCMs), ... D., Wang, Z., Qiu, J., Zhang, J., et al. (2023b). Glutathione Peroxidase 3 induced ...