In December 2024, the National Comprehensive Cancer Network® (NCCN) added AUCATZYL (obecabtagene autoleucel) to its Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for the treatment of ...

uk-erlangen.de Background Congenital malformations involving the Müllerian ducts are observed in around 5% of infertile women. Complete aplasia of the uterus, cervix, and upper vagina, also termed ...

U.S. commercial launch progressing on track with 33 authorized treatment centers as of March 19, 2025, following US FDA approval on November 8, 2024Obe-cel MHRA and ...

Expansion of CAR-T cells paralleled with the complete depletion of circulating B cells. B cell aplasia lasted for 119 days in patient 1, while patient 2 is still in B cell aplasia (day 60). Both ...

Erythropoiesis is the process by which red blood cells (erythrocytes) are produced. During human foetal development, erythropoiesis first occurs in the yolk sac, then in the foetal liver and then ...

1 Department of Clinical Genetics, Addenbrooke’s Hospital, Cambridge, UK 2 Department of Medicine, University of Cambridge, Addenbrooke’s Hospital Correspondence to: Dr S M Park Department of Clinical ...

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex.

Expansion of CAR-T cells coincidence with the complete depletion of circulating B cells. B cell aplasia lasted for a median of 120 days (range 58-205). All patients experienced drug-free remission as ...