Despite recognizing an epitope on HIV-1 gp41 that partially overlaps with those from broadly neutralizing antibodies, mAb 13H11 is non-neutralizing. Now the crystal structure and binding studies ...

In the September 25 PNAS online, researchers led by Chris Dealwis at the University of Tennessee in Knoxville published the first crystal structure of a monoclonal antibody to the amyloid-β (Aβ) ...

Researchers have now visualized the molecular structure of the LAG3 protein. They describe the crystal structure of LAG3 and how it interacts with molecules produced by cancer cells.

The two types of antibody crystal structures solved by the team revealed exactly how different amino acids are arranged around the phosphohistidine to bind it tightly.

Salk scientists defined how antibodies can recognize a compound named phosphohistidine, which plays a major role in liver, breast cancer and neuroblastoma. These insights not only set up the ...

Treatment for heparin-induced blood disorder revealed in structure of antibody complex. ScienceDaily . Retrieved April 21, 2025 from www.sciencedaily.com / releases / 2015 / 10 / 151006132033.htm ...

This paper presents the X-ray crystal structure of the complete extracellular portion of SIRP? co-crystallized with the Fab fragment of the OX117 monoclonal antibody. ... Crystal Structure of Signal ...

Crystal structure: An antibody (red and green) binds to the HCV surface protein "E2" (purple). (IMAGE) German Center for Infection Research ...

Crystal structure and biolayer interferometry of germline VRC01 binding 426c core immunogen. Image provided by Connor Weidle. In this study, the authors characterize how immunogens that better mimic ...

The crystal structure shows a significant stabilization of the H1 helix. It also shows that amino acids 197-205, which form part of a disordered segment of human PrPc that may promote β-sheet ...