All four patients (table 1, fig 1) were scheduled to receive mitoxantrone according to our protocol. None of the patients had a history of cardiac disease, cardiovascular risk factors or pretreatment ...

Adjuvant use of anthracycline–taxane combination therapy is an accepted strategy in the management of high-risk early-stage breast cancer. However, the introduction of this regimen raises the ...

As their use increased, however, it became evident that anthracyclines carry a risk of cardiotoxicity, which in some cases could be irreversible, as well as a risk of secondary leukemia.

A non-exhaustive list of examples of drugs that combine anticancer and immunostimulatory effects includes: imatinib mesylate, cyclophosphamide, anthracyclines and 5-fluorouracil. Imatinib mesylate ...

Alemtuzumab is given as an infusion, similar to glatiramer acetate. However, the alemtuzumab infusion takes four hours. Mitoxantrone hydrochloride was originally approved as a chemotherapy treatment, ...