Provision of written informed consent by patients themselves or their legally acceptable representative. Age ≥20 years at the time of consent. New diagnosis of ANCA-associated vasculitis (MPA, GPA or ...

Background: Complement fragment C5a is strongly linked to the pathogenesis of Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis (AAV). C5a receptor (C5aR), present on neutrophils, is a ...

Objective CD14+ monocytes, play pivotal role, in SLE pathogenesis through enhanced production of B-cell activating factor (BAFF), a major cytokine driving B-cell maturation into ...

Behçet's disease (BD) is a multisystem inflammatory disorder currently classified as a vasculitis. Its etiopathogenesis is unclear, but environmental, genetic and autoimmune factors have been ...