Three patients relapsed (after 12, 16, and 24 months, respectively) following elevated ANCA titers; all experienced a sustained response to repeat rituximab therapy. ANCA-titer elevations in four ...

And subsequently, several days later, her anti-PR3 titers return positive at 340 with a C-ANCA titer of 1:320. And the remainder of her serology is most notably the anti-GBM, but also ANA ...