资讯

ANCA相关性小血管炎性肾损害的治疗分为三个阶段:诱导缓解、维持缓解的治疗以及复发的治疗。诱导期通常维持3~6个月,必须持续至病情缓解为止,病情缓解后维持治疗时间一般持续24个月左右。目前,ANCA相关性小血管炎性肾损害仍无标准的治疗方案,糖皮质激素 ...
Patients with AAV are associated with an increased risk for MI, particularly during the first 3 months after diagnosis.
Antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) is characterised by a small to medium-size vasculitis and the presence of ANCA. AAV includes microscopic polyangiitis (MPA), ...
The histopathologic features of eosinophilic angiocentric fibrosis overlap with IgG4-RD and AAV, making diagnosis difficult.
Patients with AAV who received avacopan vs standard glucocorticoid-based regimens had lower exposure-adjusted rates of AEs, infections, and neutropenia/lymphopenia.
A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on the left side. Computed tomography showed a nasopharyngeal mass. A diagnosis was made.
Objective Treatment-refractory antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a life-threatening condition without evidence-based treatment options. One emerging treatment ...
Objective To compare acute treatment responses and long-term outcome in leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 patients with LGI1 ...
Iluzanebart’s failure is another ding for a TREM2 space that has already seen a recent high-profile failure. Last November, Alector’s TREM2 antibody failed its own Phase II study for Alzheimer’s ...
All responders remain in response as of a median 8.5 month follow-up, with a median time to first response of 1.2 months. The Phase I trial, initiated in November 2022, has enrolled 126 patients as of ...