ANCA相关性小血管炎性肾损害的治疗分为三个阶段：诱导缓解、维持缓解的治疗以及复发的治疗。诱导期通常维持3~6个月，必须持续至病情缓解为止，病情缓解后维持治疗时间一般持续24个月左右。目前，ANCA相关性小血管炎性肾损害仍无标准的治疗方案，糖皮质激素 ...

Among the 6 cases showing ANCA fluorescence on ethanol- or formaldehyde-fixed substrate slides, 16.7% tested strongly positive for antiproteinase 3 antibody by ELISA. Infection with the Omicron ...

Objective To assess the clinical features, pathological presentations, treatments and outcomes of lupus nephritis (LN) with anti-neutrophil cytoplasmic antibody (ANCA) positivity. Design A ...

Recent randomized, controlled trials suggest that B-cell-depletion therapy with rituximab effectively induces remission in anti-neutrophil-cytoplasmic-antibody-associated vasculitis but is ...

Objective Treatment-refractory antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a life-threatening condition without evidence-based treatment options. One emerging treatment ...

mumc.nl Background: Antineutrophil cytoplasmic antibodies (ANCA) with a C-ANCA or P-ANCA pattern are detected in ANCA-associated vasculitis (AAV). While in most patients with AAV a C-ANCA pattern is ...

Background: Complement fragment C5a is strongly linked to the pathogenesis of Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis (AAV). C5a receptor (C5aR), present on neutrophils, is a ...

这类疾病病因不明，病情进展往往难以预测，严重威胁患者的生命健康。其中，抗中性粒细胞胞浆抗体（anti-neutrophil cytoplasmic antibody, ANCA）阳性的间质性肺病（interstitial lung disease, ILD）患者，虽无系统性血管炎证据，但却被归类为孤立性 ANCA 阳性特发性间质性 ...

SLE: Systemic Lupus Erythematosus; SSc: Systemic Sclerosis; RA: Rheumatoid Arthritis; ANCA-associated vasculitis: Anti-Neutrophil Cytoplasmic Antibody associated vasculitis. (Figure created with ...

A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on the left side. Computed tomography showed a nasopharyngeal mass. A diagnosis was made.

Patients with AAV who received avacopan vs standard glucocorticoid-based regimens had lower exposure-adjusted rates of AEs, infections, and neutropenia/lymphopenia.

OSAKA, Japan & BOSTON, MA, USA I June 23, 2025 I Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”) and ...