IL-10–secreting B lymphocytes and peritoneal macrophages are activated by immunization with amyloid fibrils composed of short peptides resulting in reduction of paralysis and inflammation in mice with ...

These fragments aggregate into amyloid fibrils, forming cellular inclusions that are hallmarks of HD pathology. The propensity of polyQ proteins to aggregate correlates with tract length, which ...

For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...

SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China SKL of ...

The assembly of the NM construct produced lamellar cross-β-sheet amyloid fibrils based on transmission electron microscopy (TEM), Congo red binding, X-ray fibril diffraction and atomic force ...

In this work, we demonstrate the ability of lysozyme amyloid protein fibrils to possess piezoelectric capabilities when assembled into a freestanding bulk material. We transformed hen egg white ...

In previous research, the team loaded cultured microglial cells with smaller bits of plaques, called amyloid fibrils. When the researchers did this, the cells took a long time to break them down ...

Arctic therapeutics raises funding from EIC Fund, Kaldbakur, and Sanos Group to advance its dementia treatment, AT-001, and acne drug, AT-004. The company aims to transform the treatment landscape for ...

Transthyretin (TTR): A protein that can misfold and form amyloid fibrils, leading to amyloidosis. Gene silencers: Therapeutic agents that reduce the expression of specific genes, in this case ...

Exercise may positively influence the interactions between brain cells in the hippocampus, a brain region involved in ...

The Amyloid—Tangle Connection. Aβ aggregates (green) hyper-excite neurons in tau epicenters and connected regions, strengthening that connectivity. This pushes tau propagation from one region to ...