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基于智能储库和亲水凝胶微针的阿米替林透皮控释系统研究
本研究由来自英国和比利时的研究团队开展,旨在通过智能储库(SmartReservoirs, SRs)和亲水凝胶微针(Hydrogel-Forming Microneedles, HF-MNs)技术,实现亲水性模型药物阿米替林(Amitriptyline Hydrochloride, AMT)的透皮控释。研究发现,SRs能够显著提高药物的溶解度,并通过HF ...
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