A key protein that plays a critical role in nicotine addiction--the alpha-7 receptor--could also be a key player in the fight against obesity, Alzheimer's, schizophrenia and a long list of other ...

This exploratory trial was conducted to test the effects of an alpha7 nicotinic receptor partial agonist, TC-5619, on cognitive dysfunction and negative symptoms in subjects with schizophrenia.

A very similar receptor exists in humans. The alpha-7 receptor is the most enigmatic of the so-called "nicotinic" receptors, so named because nicotine binds to them when it is introduced into the ...

The gene, CHRFAM7A, is a fusion of a gene that codes for the Alpha 7 receptor for acetylcholine, a neurotransmitter involved in memory and learning, and long associated with Alzheimer’s and a kinase, ...

First in human trial of a type I positive allosteric modulator of alpha 7-nicotinic acetylcholine receptors: pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288.

The low affinity class of nicotinic receptors contains the alpha-7 subunit, which is present in reduced numbers in people with schizophrenia.

OSE-127/S95011 is a monoclonal immunomodulatory antibody targeting the CD127 receptor, the alpha chain of the interleukin-7 receptor (IL-7R) that induces a powerful antagonist effect on effector T ...

The team produced the world's first high-resolution images of the α7 (Alpha 7) receptor, a molecule responsible for transmitting signals between neurons – particularly in regions of the brain ...

The team produced the world's first high-resolution images of the α7 (Alpha 7) receptor, a molecule responsible for transmitting signals between neurons -- particularly in regions of the brain ...

They have produced the first high-resolution image of the α7 (Alpha 7) receptor, which transmits signals between neurons in areas of the brain responsible for learning and memory.