for monomer ensemble movements (Figure S7); DCCM for enzyme–substrate complex and product glycosyl enzyme state (Figure S8); propeptide length distribution of endo-β-1,4-xylanases (Figure S9); ...

We demonstrate that the PgaCD machinery is a novel type c‐di‐GMP receptor, where ligand binding to two proteins stabilizes their interaction and promotes enzyme activity. This is the first example of ...

Department of Chemistry, Princeton University, Princeton, New Jersey 08544, Lewis-Sigler Institute for Integrative Genomics, Princeton, New Jersey 08544, and Department of Chemistry, Boston College, ...

The authors present a computational pipeline for the identification of endogenous allosteric modulators of GPCRs, with experimental validation performed in a yeast system. This approach is valuable ...

[panjanek] came up with a relatively flexible answer to this question, building an RGB LED matrix that can display the GIFs of your choice. The web interface accepts GIFs for display. [panjanek ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) have now derived universal ...

Liver enzymes help the liver perform these functions by speeding up chemical reactions. Elevated liver enzymes happen when there are higher-than-normal levels of liver enzymes in your blood.

Assembly instructions for enzymes Universal rules can help to design an optimal enzyme from scratch Date: May 23, 2025 Source: Max Planck Institute for Dynamics and Self-Organization Summary: In ...

Beyond its enzymatic role, UBIAD1 serves as a key regulator of the endoplasmic reticulum (ER)-localized enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), the rate-limiting enzyme in the ...