Department of Chemistry, Princeton University, Princeton, New Jersey 08544, Lewis-Sigler Institute for Integrative Genomics, Princeton, New Jersey 08544, and Department of Chemistry, Boston College, ...

† Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States ‡ National Biomedical Computation Resource, University of California, San ...

Beyond its enzymatic role, UBIAD1 serves as a key regulator of the endoplasmic reticulum (ER)-localized enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), the rate-limiting enzyme in the ...

The authors present a computational pipeline for the identification of endogenous allosteric modulators of GPCRs, with experimental validation performed in a yeast system. This approach is valuable ...

We demonstrate that the PgaCD machinery is a novel type c‐di‐GMP receptor, where ligand binding to two proteins stabilizes their interaction and promotes enzyme activity. This is the first example of ...

Liver enzymes help the liver perform these functions by speeding up chemical reactions. Elevated liver enzymes happen when there are higher-than-normal levels of liver enzymes in your blood.

Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme, as a third structural component of ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Neurosterix has stepped out of the shadows with $63 million from a first-round financing led by life sciences investment group Perceptive Advisors that will be used for a portfolio of allosteric ...

[panjanek] came up with a relatively flexible answer to this question, building an RGB LED matrix that can display the GIFs of your choice. The web interface accepts GIFs for display. [panjanek ...