Liddle syndrome is an autosomal dominant disorder caused by hyperactivity of the amiloride-sensitive sodium channel (ENaC) of the principal cell of the cortical collecting tubule. In 1963 ...

At least partial autonomy of cortisol production (either direct from the adrenal cortex or secondary to adrenocorticotropic hormone secretion) Failure to suppress cortisol levels below 50 nmol/l ...

51-year-old female undergoing resection of a left adrenal cortical adenoma was incidentally found to have a periaortic retroperitoneal mass during surgery. A middle-age male patient with lytic ...