The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China Background: Ferroptosis is a regulated form of cell death characterized by ...

Background: Ferroptosis, an iron-dependent form of regulated cell death, has garnered significant attention as a potential therapeutic target in oncology due to its unique mechanism involving lipid ...

Announcing a new publication for Acta Materia Medica journal. Tumor ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has emerged as a promising therapeutic ...

Find more information on the Altmetric Attention Score and how the score is calculated. Ferroptosis is a nonapoptotic, iron-catalyzed form of regulated necrosis that is critically dependent on ...

Herein, by harnessing the recently discovered oxidative stress regulation ability of p53 and the Fenton reaction inducing capability of metal–organic network (MON), MON encapsulated with p53 plasmid ...

These cells are consequently more sensitive to ferroptosis, a cell death process catalyzed by iron, which causes oxidation and the degradation of membrane lipids. Thanks to innovative chemistry ...

This crucial advance in the fight against metastatic cancer is based on identifying the cellular site for ferroptosis initiation, a natural process, catalyzed by iron, that sparks the oxidative ...

This study presents a useful finding for the ferroptosis-mediated tumor microenvironment (TME) in triple-negative breast cancer (TNBC) using public single-cell RNA sequencing (scRNA-seq) and bulk RNA ...

This work was supported by Deutsche Krebshilfe (70115440) to D.K. and the European Research Council under the European Union’s Horizon 2020 research and innovation program (Grant Agreement No. GA ...

Purpose: To reveal the role and underlying mechanism of hirudin in renal fibrosis. Methods: The unilateral ureteral obstruction (UUO) rat model and ferroptosis activator RSL3-induced human kidney ...