How do cells forming organs or repairing tissues know when to stop growing? Adhesion receptors act as molecular fingertips that sense the environment and then coordinate behaviors. Aa Aa Aa In ...

How do cells forming organs or repairing tissues know when to stop growing? Adhesion receptors act as molecular fingertips that sense the environment and then coordinate behaviors.

Adhesion G protein-coupled receptors (aGPCRs) are the second largest family of these receptors in humans. As their name suggests, they help cells adhere (stick to each other), and send signals ...

the researchers used human breast cancer cells depleted of junctional adhesion molecule-A (JAM-A), a cell adhesion receptor that is localized at cell-cell junctions in polarized epithelial cells.

β2-Integrin Adhesion Regulates Dendritic Cell Epigenetic and Transcriptional Landscapes to Restrict Dendritic Cell Maturation and Tumor Rejection. Cancer Immunology Research , 2021; DOI: 10.1158 ...

At cell-cell junctions, adhesion receptors at the cell surface are linked via adaptor proteins to the cytoskeleton, a structural scaffold inside the cell composed of filamentous proteins like actin.

Adhesion GPCRs (aGPCRs), which comprise 33 receptors, participate in a variety of physiological processes such as immune responses, organ development and cellular communication. These receptors ...

The force direction between ligand and receptor is tangential to the cell or parallel to the substrate, leading to different cell adhesion behavior. Preliminary studies showed that integrins ...

It is known that integrin receptors send important signals into the cells and when these are missing cancer cells no longer effectively form tumors. However, it turns out that this can also ...

In the lead story, Kimberly Maguschak and Kerry Ressler of Emory University in Atlanta, Georgia, implicate the adhesion receptor and signaling molecule β-catenin in the synaptic restructuring that ...