Activin A在NEC模型小鼠肠道组织中表达上调 ELISA和WB显示NEC组Activin A蛋白水平显著高于对照组，免疫组化证实其定位在肠上皮和炎症浸润区域。 Activin A加剧NEC病理进程 ...

Keros still has future revenue opportunity from the activin receptor type IIA (ActRIIA) fusion protein elritercept, which Takeda licensed for development in myelodysplastic syndromes and myelofibrosis ...

Pituitary tumor They tend to be more common in females and make up 9% to 12% of all primary brain tumors. They grow slowly, though larger tumors can create pressure on surrounding areas of the brain.

Regeneron is paying Hansoh Pharma $80 million upfront for a phase 3-stage GLP-1/GIP receptor agonist the companies believe can hold its own against Eli Lilly’s Zepbound.. As well as the upfront ...

PASADENA, Calif., June 02, 2025--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced that it has dosed the first subjects in a Phase 1/2a clinical trial of ARO-ALK7, the company’s ...

TARRYTOWN, N.Y., June 02, 2025 (GLOBE NEWSWIRE) -- Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced interim results from the ongoing Phase 2 COURAGE trial investigating novel ...

Pointing to safety data, however, BMO noted that “safety for myostatin activin treatment may still be in question,” since 10.1% experiencing severe adverse effects and 28.3% stopping treatment ...

In this study, molecular docking and molecular dynamics (MD) simulations were conducted to investigate both the binding site and interactions of 61 inhibitors with activin-like kinase-5 (ALK5) ...

18. Gebel P. Pituitary apoplexy: review of literature with a report of an unusual case associated with diabetes insipidus. Mil Med 1962;127:753-760. 19. Yue H, Huaqiu Z, Yong L, et al .The observation ...

为解决B细胞急性淋巴细胞白血病(B-ALL)中枢神经系统(CNS)浸润机制不明的问题，意大利研究团队开发了三维(3D)离体脑切片模型，通过微注射人B-ALL细胞系NALM6，发现促白血病因子Activin A可加剧白血病细胞增殖并诱导脑组织死亡，同时重塑小胶质细胞和星形胶质细胞的抗炎表型。