During embryonic development, thousands of cells divide and move collectively, sculpting the main body axes from an initially ...

Department of Biomedical and Molecular Sciences, Queen’s University, 18 Stuart Street, Kingston, ON K7L 3N6, Canada ...

Andrew T. Lombardo, PhD, assistant professor of biochemistry, has received a $1.9 million National Institutes of Health grant to study cell polarity signaling.

The findings in this manuscript are fundamental because they identify an entry receptor MYL3 that belongs to the myosin family as a possible target that could inhibit ... treated with Triton X-100 or ...

We elucidate the mechanism of the remodeling by combining computer simulations with protein array experiments and electron microscopic imaging, to arrive at a structural model for the dodecameric ...

Here, we used a standard gliding motility assay to study the actin filaments sliding on a surface comprising heavy mero myosin (HMM) micro- and nano-patterns. To print HMM, we used negative tone, ...

The utility of the approach is demonstrated by quantifying the α and β protein isoforms of myosin heavy chain (MyHC) in human atrial tissue. α-MyHC (726−741) and β-MyHC (724−739) were identified as ...

making it difficult to assess any physiological function of this signaling complex independent of localization. Here we demonstrated that INAD bound directly to the NINAC myosin III, yet the ...