The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as one-dimensional tracks on which motor proteins move.

No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

Each cylindrical tube is filled with parallel rods of actin filaments bundled by cross-linking proteins. Filamentous actin is a chemical motor; the energy released upon synthesis and breakdown of ...

Vale became intrigued by microscopy movies generated by his lab neighbors James Spudich and visiting professor Michael Sheetz showing myosin-coated beads moving along the actin cables of purified ...