The authors reveal a conserved mechanism through which the nutrient sensor PKA phosphorylates Rpd3/HDAC1 to inhibit its ability to deacetylate SAGA complex and enhance nucleosome acetylation ...

School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China ...

The improvement of properties in nanocomposites obtained by topochemical surface modification, e.g., acetylation, of the nanoparticles is often ascribed to improved compatibility between the ...

Microtubule acetylation is essential for many cellular functions and has been linked to various health conditions, including cancer and brain disorders. Until this study, the molecular mechanism ...

Cancer plasticity allows tumor cells to change their identity, evade therapies, and adapt to environmental pressures, contributing to treatment resistance and metastasis. New research is targeting ...

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30% of their body weight in just one week, a new study shows.

Experiments showed that lowering cysteine levels caused a drop in levels of the small molecule called coenzyme A (CoA), which rendered inefficient mechanisms ... degradation of acetyl-CoA ...

Have you ever stared blankly at a screen, forgotten simple tasks, or struggled to articulate your thoughts during a meeting? These moments of mental lapse might seem harmless at first, […] ...

DelveInsight’s, “Diffuse Large B-Cell Lymphoma Pipeline Insight 2025” report provides comprehensive insights about 70+ ...

The mechanism behind Breathe Lung Supplement revolves around a three-phase approach to respiratory support. In the first ...

本研究针对精子功能中蛋白乙酰化（acLys）的关键作用，探索了在碱性pH条件下非酶促乙酰化机制对受精能力的影响。研究人员通过抑制乙酰转移酶（KATs）并模拟体内pH变化，发现α-微管蛋白（α-tubulin）在精子中段特异性乙酰化与运动能力下降相关，同时揭示了 ...