Histologic evidence of acantholysis is diagnostic. This is an acute disease with involvement of mucous membranes and skin without vesicles and bullae. The patients are constitutionally ill ...

This case suggests that: (1) manicure procedures may trigger underlying genetic skin conditions through mechanical injury or chemical irritation; (2) nail fold infections complicated by acantholysis ...

This case suggests that: (1) manicure procedures may trigger underlying genetic skin conditions through mechanical injury or chemical irritation; (2) nail fold infections complicated by acantholysis ...

[1] This detachment (called acantholysis) is due to the presence of IgG antibodies directed against keratinocyte-adhesion glycoproteins, called desmogleins (DSG), which play a critical role in ...

I believe that alternative therapies fostering keratinocyte adhesion and/or specifically antagonizing the effects of pemphigus antibodies can be developed based on: (1) elucidation of the mechanism of ...

Your healthcare provider will look for acantholysis of your skin cells. Acantholysis occurs in groups of cells due to a loss of proteins that make cells stick together. Seeing acantholysis in a ...

Epidermolysis bullosa is a rare genetic condition that makes skin so fragile that it can tear or blister at the slightest touch. Children born with it are often called “Butterfly Children ...

Model of the molecular mechanism of acantholysis in PV. Autoantibody binding to the desmosome cadherin dsg3 on the surface of epidermal keratinocytes activates sequential phosphorylation of p38MAPK, ...

Molecular mechanisms underlying auto-antibody-induced acantholysis in pemphigus vulgaris are subject of current research to date. To decipher the discrepancy between ubiquitous antibody binding to the ...

Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilians-Universität Munich, Munich, Germany Desmosomes have been studied extensively in recent years in consequence ...

The epidermis demonstrated spongiosis, erosion, and vesicles with mild keratinocyte acantholysis, and inflammatory cells (lymphocytes, histiocytes, and multinucleate giant cells (Figure 1). The ...