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多肽合成Lysipressin acetate;83968-49-4
抗利尿作用:通过激活肾脏集合管细胞的V2受体,刺激腺苷酸环化酶(AC)产生cAMP,促进水通道蛋白(AQP2)膜转位,增强水分重吸收。 平滑肌收缩:结合血管与内脏的V1a受体,诱导磷脂酶C(PLC)信号通路,触发兔膀胱平滑肌收缩(EC₅₀约10⁻⁸ M)。 升压效应 ...
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