The AMP-activated protein kinase (AMPK) system acts as a sensor of cellular energy status that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP:ATP ratio caused ...

2 型糖尿病患者患阿尔茨海默病（AD）风险增加，GLP-1 受体激动剂（GLP-1RAs）的抗 AD 作用及机制尚不明确。研究发现 GLP-1RAs 通过激活 CaMKK2–AMPK 通路，减少 Aβ 生成、抑制神经炎症并促进 Aβ 吞噬，改善 AD 模型小鼠表型，为 AD 治疗提供新方向。 2 型糖尿病个体患 ...

本研究针对心肌缺血再灌注(I/R)损伤的治疗难题，探索了骨髓间充质干细胞外泌体(BMSCs-Exo)通过激活AMPK/PGC-1α信号通路改善心肌 ...

London, UK, May 15, 2025 (GLOBE NEWSWIRE) -- In today's fast-moving crypto landscape, investors are searching for smarter ways to build resilient portfolios - and many are now turning to DN Miner, a ...

During the intervening night of 07-08 May 2025, Pakistan Army posts resorted to unprovoked fire using Small Arms and Artillery Guns across the LoC in areas opposite Kupwara, Baramulla, Uri and ...

At least 12 civilians, including three women and three children, were killed, and 51 others injured as the Pakistan Army resorted to heavy mortar shelling and firing on villages, hitting scores of ...

Medical experts have warned that ending fluoridation will have negative consequences for oral health. By Emily Cochrane Gov. Ron DeSantis of Florida signed a bill into law on Thursday that bans ...

Your co-worker surprised you with a chocolate chip cookie, but a teammate took a dig at your report. As the day goes on, you’re more likely to dwell on the criticism than the act of kindness ...

Mark Zuckerberg wants you to have AI friends, an AI therapist and AI business agents. In Zuckerberg’s vision for a new digital future, artificial-intelligence friends outnumber human companions ...

A SpaceX Falcon 9 rocket prepares to launch a rapid-response Space Force mission from Cape Canaveral Space Force Station, Florida. (Lockheed Martin) Reduced launch costs over the last few decades ...