Western blotting and immunofluorescence staining were used to detect biomarker proteins of ferroptosis, inflammation, and AMPK/Nrf2/GPX4 signaling pathway proteins. Results: The results showed that ...

The glucagon-like peptide-1 (GLP-1) agonists liraglutide and Ex-4 activated the expression of peroxisome proliferator-activated receptor alpha (PPARα) via a GLP-1 receptor-dependent 5′ AMP-activated ...

Apoptosis, epithelial-mesenchymal transition, and related molecular pathways were analyzed by western blot. Wound healing assays and Transwell migration assays examined cell migration, whereas ...

New research suggests that drugs like Ozempic may provide more health benefits than previously thought. These medications, ...

近年来，随着医学领域对中药药理作用的认识不断深化，中药在慢性疾病管理中的独特优势已获得国内外医学界的广泛认可。临床证据表明，津力达颗粒的应用降低了代谢异常受试者患糖尿病的风险[1]，还有利于改善糖尿病肾脏病（DKD）患者的肾功能[2]，但其具体的作用 ...

Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

2024年11月14日，吉林大学第一医院肾内科在Scientific Reports（中科院二区 IF=3.8）期刊上在线发表题为"Ulinastatin attenuates renal fibrosis by regulating AMPK/HIF-1α signaling pathway-mediated glycolysis"(乌司他丁通过调节 AMPK/HIF-1α ...