Panelists explain that KMT2A-rearranged acute myeloid leukemia (AML) is an aggressive, molecularly distinct leukemia subtype marked by menin-dependent transcriptional dysregulation, poor response ...

Some of these genes may be directly implicated in the pathogenesis of AML and in addition, several of them encode for proteins, which are known therapeutic targets.

Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear. We ana ...

Understanding the fundamental molecular mechanisms underlying normal hematopoiesis and AML pathogenesis can aid the development of novel and effective targeted therapies.

Understanding the fundamental molecular mechanisms underlying normal hematopoiesis and AML pathogenesis can aid the development of novel and effective targeted therapies. Prof.

An uptick in fines associated with anti-money-laundering failures demonstrates that U.S. banks still have much work to do in terms of optimizing their internal systems to identify and stop the flow of ...

Leukemia is a type of cancer that attacks blood-forming cells in the bone marrow. There are two types of rapidly progressing, or acute, leukemia: ALL and AML. Find out how they're similar to and ...

An established oncogenic driver of AML pathogenesis is the FLT3 protein, which previous work has shown to be frequently mutated in AML cells.

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

Panelists highlight that the emergence of menin inhibitors is reshaping the treatment paradigm for KMT2A-rearranged acute myeloid leukemia (AML), with ongoing research focused on optimizing their use, ...

A jury in California convicted Rowland Marcus Andrade of wire fraud and money laundering in connection with the sale of AML Bitcoin.

Acute myeloid leukemia, or AML, is a type of cancer that affects the bone marrow and blood. Learn about outlook and survival rates for this cancer.