Panelists explain that KMT2A-rearranged acute myeloid leukemia (AML) is an aggressive, molecularly distinct leukemia subtype marked by menin-dependent transcriptional dysregulation, poor response to ...

Aberrant DNA methylation patterns are a characteristic feature of cancer including myeloid malignancies such as acute myeloid leukemia (AML). The mechanisms behind aberrant DNA methylation have ...

为探讨 AML 非强化治疗中出现可靶向克隆时的策略、MRD 检测应用等问题，研究人员分析相关疗法及生存数据。发现 Ven-Aza 序贯治疗或三联疗法可优化方案，MRD 检测仍需完善，AML 生存率显著提升。研究为临床提供方向。 急性髓系白血病（acute myeloid leukemia ...

This issue becomes even more paramount for businesses using anti-money laundering (AML) tools, where the backbone of the AI solution, an AML data layer, is often weak or poorly structured.

急性髓系白血病（AML）预后差、复发率高，表观遗传调控中的 RNA 甲基化备受关注。研究人员聚焦甲基转移酶样蛋白（METTL）家族，发现 METTL13 在 AML 中高表达且与预后不良相关，其通过调控 MYC 影响 AML 细胞增殖与存活，为 AML 治疗提供新方向。 急性髓系白血病 ...

The European Commission has approved Astellas’ Xospata (gilteritinib) for patients with relapsed or refractory FLT3-positive acute myeloid leukemia (AML), cementing its lead over a rival drug ...

Cancer pathogenesis is a pathophysiological understanding of how molecular and cellular events play a causal role in transforming tumors from benign to malignant state. This often involves genetic, ...

The KOMET-001 trial is a pivotal study evaluating ziftomenib, a daily oral menin inhibitor, for the treatment of relapsed/refractory (R/R) NPM1-mutant (NPM1-m) acute myeloid leukemia (AML).