Adcock Ingram’s efavirenz product is currently awaiting ... existing range of 1st line HIV treatments that are available: Adco-Lamivudine, Adco-Zidovudine and Adco-Nevirapine.

Patients were randomly assigned to receive, in addition to two nucleoside analogues, nelfinavir, efavirenz, or nelfinavir plus efavirenz. The primary end point was a plasma HIV-1 RNA level of less ...

Patients stopping efavirenz-based combination therapy might be well advised to continue their NRTIs for 24 to 48 hours after discontinuing efavirenz to avoid prolonged NNRTI monotherapy.

Credit: FDA. The Warnings and Precautions section has been updated to address the potential for late-onset neurotoxicity, including ataxia and encephalopathy with efavirenz treatment. The Warnings ...

But in parts of South Africa where teenagers are smoking it to get high, Efavirenz is a dangerous drug with the deadly potential to destroy lives. When crushed up and smoked, the inexpensive ...

"The pendulum has swung back and forth over the years regarding efavirenz use in pregnancy because of concern about potential teratogenicity," said Gail Shust, MD, a from Hassenfeld Children's ...

These findings, among others in the paper, may pave the way to developing drugs that mitigate brain toxicities associated with Efavirenz. (ACS Pharmacol. Transl. Sci. 2024, 7, 8, 2379-2390 ...