Figure 1: Neuroprotection by bFGF is associated with increased expression of activin βA mRNA. Recently, a different type of interaction between bFGF and the TGF-β superfamily was reported from ...

1 Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States 2 Department of Urology, Beth Israel Deaconess Medical Center and Harvard Medical ...

After bringing Zolgensma to market in 2019 as the first gene therapy for spinal muscular atrophy, Novartis is back with a ...

Activin A 是一种多功能细胞因子，是TGF-β 超家族的成员。Activin A 首先与成员表面的 II 型激活素受体 (ActIIRA 或 ActRIIB) 结合，然后募集和磷酸化 I 型激活素受体 (ActRI)。Activin A 主要通过SMAD2/3 蛋白发出信号以调节多种功能，包括炎症、纤维化和肿瘤发生。 Activin以三 ...

The challenge of the obesity epidemic is widespread and one that even pediatricians face constantly,” a Connecticut doctor ...

Reuters, the news and media division of Thomson Reuters, is the world’s largest multimedia news provider, reaching billions ...

Keros Therapeutics' stock has plummeted over 70% due to safety issues in its phase 2 PAH study, halting all trial arms. Learn more about KROS stock here.

近日，国家卫生健康委员会主任宣布将持续推进“ 体重管理年”行动，鼓励医疗机构设立体重门诊，采用多学科干预手段帮助患者减重。这一举措无疑为减重市场注入了强大的动力，也预示着肥胖治疗领域即将迎来一场前所未有的变革。

为探究黑色素瘤中激活素 A（Activin-A）前体加工机制及对肿瘤生长影响，研究人员经 RNAi 筛选等研究，发现 Klk8 可调节其加工促肿瘤生长，为治疗提供新靶点。 在人体中，有一种名为激活素 A（Activin-A）的蛋白质，它属于转化生长因子 -β（TGF-β）家族，就像一个 ...

Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced presentation of preclinical data supporting the advancement of ...

Hormones can be paracrine, endocrine or autocrine factors. The Activin-A precursor protein undergoes proteolytic processing by furin and other proteases. Here the authors identify that kallikrein ...

About a dozen drugmakers are developing new weight-loss treatments aimed at preserving muscle, and industry analysts, clinical trial experts and doctors say they may also need to demonstrate ...