To bring this strategy closer to clinical application, we now show that neurogenesis can also be stimulated when delivering these transcription factors to Müller glia using adeno-associated viral (AAV ...

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Maple syrup urine disease (MSUD) is a rare genetic inborn error of metabolism characterized by recurrent life-threatening neurologic crises and progressive brain ...

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AAV vector titers (viral particles (vp)/ml) were determined by quantitative PCR for viral genome copies extracted from DNAase-treated viral particles (High Pure Viral Nucleic Acid Kit, Roche). The ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

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