Military probe finds Yamam and Shin Bet officers' actions halted Hamas's advance during onslaught, enabled troops to reach other areas under attack ...

"znf385a缺失增强5-aza-cdr和nk细胞疗效"：tcga数据分析显示znf385a在21种癌症中高表达且与nk细胞浸润负相关。 功能实验证实敲除细胞对DNA甲基化抑制剂5-AZA-CdR敏感性提高，与NK92细胞共培养时肿瘤杀伤效率提升40%，添加IFNβ可进一步增强该效应。

该研究不仅拓展了dsRBP数据库，还为肿瘤免疫治疗中5-AZA-CdR与NK细胞的协同作用提供了新靶点。 在生命科学领域，双链RNA(dsRNA)作为病毒感染的典型分子标志物，其识别和调控机制一直是先天免疫研究的核心问题。传统认知中，dsRNA主要通过RIG-I样受体(RLRs) ...

Moreover, the addition of vitamin C, a required co-factor for TET enzyme based DNA demethylation provides a synergistic effect of 5-Aza-CdR treatment (Liu et al., 2016). Most cancer patients are ...

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。 Decitabine. 品牌：MedChemExpress (MCE) CAS：2353-33-5 纯度：0.9987 货号：HY-A0004 中文名称：地西他滨；地西他宾；2'-脱氧-5-氮杂胞啶；2'-脱氧-5-氮杂胞啶 Synonyms：地西他滨; 5-Aza-2'-deoxycytidine; ...

Vitamin C and 5-aza-CdR therefore synergistically up-regulate the cytosolic viral RNA defense pathways, strengthening the viral mimicry state produced by DNMTi treatment alone (12, 13). Combination ...

To validate this, we assessed the 5-aza-dC sensitivity of DCTD knockout (KO) HAP1 cells in clonogenic survival assays and observed profound 5-aza-dC resistance compared to wild-type (WT) cells, while ...

According to local Israeli outlet i24News, Israel Defense Forces (IDF) soldiers moved into Kfar Aza, one of the communities Hamas terrorists invaded early Saturday morning, and discovered about 40 ...