A new study published in the journal Brain Research provides evidence that chronic use of a lipid-based cannabidiol (CBD) nanoemulsion may help reduce anxiety and panic-like behavior by targeting ...

† Department of Biological Sciences, St. Mary’s University, San Antonio, Texas 78228, United States ‡ Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77840, ...

While there are many grades of CAH severity, they all involve excess androgens (male sex hormones like testosterone). Up to 95% of CAH cases involve a 21-hydroxylase deficiency, a key enzyme for ...

Classical forms of congenital adrenal hyperplasia are caused by a severe deficiency of 21-hydroxylase, an enzyme involved in steroid biosynthesis, which triggers excessive androgen production ...

The most common form of congenital adrenal hyperplasia (CAH) is a condition in which the deficiency of the 21-hydroxylase enzyme results in absent or very low cortisol production. CAH differs from ...

All patients were treated and were medically stable after 29 (2 - 60) months of follow up. Autoantibodies to 21-hydroxylase enzyme were positive in 16 (90%). At diagnosis, and subsequent follow up, ...

Prolyl hydroxylase domain protein 2 (PHD2, also known as egg-laying defective nine 1 ... In gastric cancer and prostate cancer, PHD2 affects tumor development by inhibiting the HIF-mediated hypoxia ...

From the Departments of Medicine (F.R., L.Z., K.Z., G.W., B.P.K., M.D., J.L.R.-F., P.E.C., R.M.S., S.K.M., L.T., M.G.Z., D.T.O.), Pharmacology (D.T.O.), Psychiatry (J ...

If you were born with nonclassical congenital adrenal hyperplasia, your body doesn’t make enough of a certain enzyme called 21-hydroxylase, which affects the amount of hormones your body makes ...

Approximately 95% of CAH cases are caused by a mutation that leads to deficiency of the enzyme 21-hydroxylase (21-OHD). In classic CAH, severe deficiency of this enzyme leads to an inability of the ...

So as to rule out an 11-beta-hydroxylase enzyme deficiency given the high blood pressure levels associated with hypokalaemia, the deoxycorticosterone (DOC) level came back high at 2599 pg/ml, i.e.

Objective: Herein, we compared ambulatory blood pressure (ABP) between young adults with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase enzyme (21OHase) deficiency and a control group.