17 Alpha-Hydroxylase Deficiency (17OHD) is a rare genetic disorder caused by mutations in the CYP17A1 gene, which plays a crucial role in steroid hormone production. This condition leads to a ...

The most common form of CAH is caused by a deficiency in the enzyme 21-hydroxylase, which is crucial for the production of cortisol and aldosterone. This condition can result in serious health ...

SAN DIEGO - Neurocrine Biosciences, Inc. (NASDAQ:NBIX) has sponsored a supplement in The Journal of Clinical Endocrinology & Metabolism (JCEM) focusing on classic congenital adrenal hyperplasia (CAH), ...

and pharmacokinetics of atumelnant when administered for 12 weeks in people with CAH caused by 21-hydroxylase deficiency. The study enrolled 28 patients across 3 dose cohorts with classic CAH on a ...

due to 21-hydroxylase deficiency. The CAHtalyst studies were the largest-ever clinical trial program in classic CAH, including 285 pediatric and adult patients. The CAHtalyst Pediatric study included ...