A cell-based screen performed in our laboratories identified a new class of Hh pathway inhibitors, 1-amino-4-benzylphthalazines, that act via antagonism of the Smoothened receptor. A variety of ...

are neither normal components of the fuel nor additives designed to improve the characteristics or the performance of the fuel; or are normal components of the fuel or additives designed to improve ...

Department of Chemistry, School of Science, Loughborough University, Ashby Road, Loughborough LE11 3TU, U.K.

1). Murine and human PD-L2 have 70% amino acid identity. This is similar to the 69% identity between human and murine PD-L1 and which is higher than the 45–51% identity between human and murine ...

Figure 1. Catabolic pathways of branched-chain amino acids (BCAAs) and downstream signaling initiated by catabolites (for explanation, see BCAA Catabolism section). 4E-BP1 indicates eukaryotic ...

1 Department of Endocrinology and Metabolism, School of Medicine, Chongqing University Central Hospital, Chongqing Emergency Medical Centre, Chongqing University, Chongqing, China 2 Department of ...