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腾讯网
3 天
北京大学基础医学院用单细胞轨迹推断发现调控脂肪生成的G蛋白偶联 ...
在高脂饮食(HFD)诱导的肥胖小鼠模型中,通过基因过表达和基因敲低实验进一步证实,ADGRD1促进脂肪生成,从而改善代谢稳态,而GPR39抑制脂肪生成,导致代谢紊乱。此外,通过分析2,400个ChIP-seq数据和1,204个RNA-seq数据,作者 ...
腾讯网
6 天
The Innovation | 新型仿生聚合前药纳米制剂用于脑缺血-再灌注损伤治疗
目前,临床上仍缺乏治疗脑缺血-再灌注损伤的有效手段。本研究将仿生技术与纳米聚合前药的优势相结合,皆在开发一种有效治疗脑缺血-再灌注损伤的新型纳米制剂,以期为脑缺血-再灌注损伤患者带来新的希望。导读脑缺血-再灌注损伤是缺血性卒中患者恢复受损脑组织血流时 ...
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