Tafamidis has made a tremendous difference in the lives of patients with ATTR-CM. Tafamidis is a key therapy in the management of transthyretin amyloid cardiomyopathy (ATTR-CM), and its approval by ...

Which of the statements below about the prognosis of generalized pustular psoriasis (GPP) are correct? Select one of the options for each question, then submit your answers to see how well you scored ...

Vosoritide therapy led to remarkable improvements in the mechanical axis angle and mechanical lateral proximal femoral angle in the younger patients. One year of treatment with vosoritide has been ...

The relationship between a parameter readily available on standard electrocardiogram and invasively measured vascular stiffness provides the opportunity to refine patient selection, monitoring, and ...

Approximately 31% of dermatologists reported difficulty with flare management, citing slow response to treatment (63%) and lack of flare prevention (66%) as key challenges. There is an urgent need for ...

Pharmacological inhibition of xCT with sulfasalazine, administered preventively or therapeutically, significantly reversed or prevented PAH-related abnormalities. The plasma membrane exchanger xCT may ...

In this study, relative residence time, which is a parameter that takes into account both oscillatory shear stress and time-averaged wall shear stress, emerged as a robust metric for evaluating ...

More standardized research is needed to guide second-line agent selection in IgG4-RD. Rituximab offers a highly effective steroid-sparing option for the treatment of immunoglobulin G4-related disease ...

Tumor-like alterations in the bladder may be a complication in patients with IgG4-RD. A middle-aged female patient with hematuria and pain over her left renal area was diagnosed with bladder ...

When the prevalence of PBC was adjusted for population size, it was found to be highest in certain rural areas. There are areas of high prevalence of primary biliary cholangitis (PBC) in some rural ...

The patient was diagnosed with primary biliary cholangitis based on blood test results showing he was positive for antimitochondrial antibody, antimitochondrial antibody-subtype 2, centromeric protein ...

Null IL36RN mutations are prevalent among East Asian patients with GPP and ACH. Marked ethnic differences in genetic background, clinical presentation, and treatment responses are apparent between ...