Although intravenous thrombolysis with alteplase remains the primary treatment for acute ischemic stroke, tenecteplase has shown potential advantages over alteplase. Animal studies have demonstrated ...

Appendix 1. Author Relationships with Industry and Other Entities (Relevant) e115 Appendix 2. Reviewer Relationships with Industry and Other Entities (Comprehensive) e117 When developing ...

To test the effects of long‐term RD on SHRcp rats, they were followed for 19 weeks after RD. SHRcp rats (n=22) were divided into 2 groups: one received bilateral RD (RD group, n=11), and the other ...

Significant mitral regurgitation (MR) is an increasingly common disorder affecting nearly 10% of the US population aged >75 years and is associated with increased morbidity and mortality in the ...

Figure 1. Attendees of The First William Harvey Workshop on Endothelin (ET-1), chaired by Sir John Vane and held at St. Bartholomew’s Hospital, London, on December 6, 1988. This meeting marked the ...

We hypothesized that high-sensitivity cardiac troponin (hs-cTn) and its early change are useful in distinguishing acute myocardial infarction (AMI) from acute cardiac noncoronary artery disease. In a ...

Graduate Program in Translational Biology, Medicine, and Health (R.L.P., G.A.B., K.E.S., D.R.K.), Virginia Tech, Blacksburg. Fralin Biomedical Research Institute at ...

In 1985 to 1986, the CARDIA (Coronary Artery Risk Development in Young Adults) study enrolled 5115 Black or White participants, including 2788 women, aged 18 to 30 years. Over the following 35 years, ...

Circadian rhythms in physiology and behavior are ≈24-hour biological cycles regulated by internal biological clocks (ie, circadian clocks) that optimize organismal homeostasis in response to ...

As early as 1699, Chemineau described a heart composed of 2 auricles but only 1 ventricle. 1 The univentricular heart has since fascinated the medical community. Unique in its complexity and scope, ...

4. Choosing the Right Pathway With Patient-Centric Algorithms for Acute Chest Pain e343 4.1. Patients With Acute Chest Pain and Suspected Acute Coronary Syndrome (Not Including STEMI) e343 4.1.1.

The interesting results of Ciaccio et al 15 may be seen as an attempt to support the notion that as AF becomes persistent, it increasingly depends on drivers localized within atrial regions outside ...