BMJ Evidence-Based Medicine (BMJ EBM) publishes original evidence-based research, insights and opinions on what matters for health care. We focus on the tools, methods, and concepts that are basic and ...

Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to ...

1 Evidence-Based Practice Center, Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA 2 Knowledge and Evaluation Research ...

Background Major depressive disorder is estimated by the WHO to affect more than 300 million people globally, making depression the leading cause of disability worldwide. Antidepressants are commonly ...

Objectives To describe the proportion of transvaginal ultrasounds performed in a University Hospital of Buenos Aires (Argentina), requested upon a health check. Method Cross-sectional study of a ...

This paper forms part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group and addresses rapid qualitative evidence syntheses (QESs), which use modified systematic, ...

Correspondence to Dr Elaine Lehane, Nursing & Midwifery, University College Cork, National University of Ireland, Cork, Ireland; e.lehane{at}ucc.ie Fostering a culture of clinical effectiveness in ...

We have evaluated dietary recommendations for people diagnosed with familial hypercholesterolaemia (FH), a genetic condition in which increased low-density lipoprotein cholesterol (LDL-C) is ...

Correspondence to Professor Kari A O Tikkinen, Department of Urology, Helsinki University Hospital, Helsinki 00290, Finland; kari.tikkinen{at}helsinki.fi To practice high quality healthcare, ...

Non-randomised studies assessing COVID-19 vaccine effectiveness need to consider multiple factors that may generate spurious estimates due to bias or genuinely modify effectiveness. These include ...

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RRs) use modified systematic review methods to accelerate the review process ...

Objectives Octopus is a new publishing platform designed to replace journals and papers as the means of sharing scientific knowledge and ideas. It is designed to serve the needs of science and ...