Heart failure is a global public health issue that is associated with increasing morbidity and mortality. Previous studies have suggested that mitochondrial dysfunction plays critical roles in the ...

The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk ...

New Cornerstone Investigator Institute, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of ...

The most common mechanism of sports-related SCD is an abrupt ventricular fibrillation attributable to a wide spectrum of underlying cardiovascular diseases. The causes reflect the age of participants: ...

Dual antiplatelet therapy (DAPT) helps prevent ischemic events after coronary stenting but comes with an increased risk of bleeding. Several risk scores have been proposed for the management of ...

A foundational concept in cardiac electrophysiology is that understanding the cellular mechanism of an arrhythmia provides essential insight for developing targeted therapeutic options. However, ...

Results are mean±SE (unless indicated otherwise). Significant differences were assigned using the paired or unpaired Student t test (as appropriate) or 1-way ANOVA and Tukey multiple comparison with ...

Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida School of Medicine, Tampa. For Sources of Funding and Disclosures, see page 1611.

Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that ...

In the article by Xue et al, “Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A–Induced Pulmonary Arterial Hypertension,” which published in the October 2020 issue ...

Medical Research Council/Uganda Virus Research Institute and London School of Hygiene & Tropical Medicine, Uganda Research Unit, Entebbe (A.J.N.).