Specifically, they were able to map proteins in defined subregions of the sarcomere, starting from the "Z-disc," the boundary between neighboring sarcomeres. This in and of itself was a ...

Z-bodies will align in the area of the future Z-disk. Sarcomere spacing then becomes increasingly regular owing to the action of the contractile forces that the myofibrils experience, through the ...

The calculated reconstruction of the myofibrils revealed the three-dimensional organization of the sarcomere, including the sub regions M-, A-, and I- bands, and the Z-disc, which unexpectedly ...

An international team has produced the first high-resolution 3D image of the sarcomere, the basic contractile ... regions M-, A-, and I- bands, and the Z-disc, which unexpectedly forms a more ...

BACKGROUND: Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation ...