Tissue-based genomic classifier tests, developed to improve prostate cancer risk assessment and treatment recommendations, ...

leading to epigenetic activation of genes encoding antigen-presentation molecules that enhances tumor immunogenicity and boosts the efficacy of immunotherapy. In an unbiased high-throughput screen ...

Chimeric antigen receptor-T (CAR-T) cell therapy ... We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy.

A new paper by a team of Concordia researchers from the departments of Biology and Physics proposes a novel method of ...

The FDA has approved a new treatment for patients with a common form of breast cancer that has spread to other parts of the body or cannot be surgically removed.

A study shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators examined how molecular dynamics at the immune synapse -- where ...