WarmStart® RTx Reverse Transcriptase, specifically designed for nucleic acid detection. Sir Richard Roberts, Chief Scientific Officer at NEB, commented on the announcement, “NEB has a 40-year history ...

In order for HIV to replicate, it uses an enzyme called reverse transcriptase to translate its viral RNA into double-stranded ...

Again, the selectivity of the inhibitory activity of AZT for a viral enzyme — HIV reverse transcriptase — compared with enzymes involved in DNA synthesis in normal cells provided a therapeutic ...

CRF: Circulating recombinant form; NNRTI: Non-nucleoside reverse-transcriptase inhibitor; NRTI: Nucleos(t)ide analog reverse-transcriptase inhibitor. Eight nucleos(t)ide analog reverse ...

A retroviral enzyme which converts genetic material from RNA into DNA, an essential step in the lifecycle of HIV. Several classes of anti-HIV drugs interfere with this stage of HIV’s life cycle: ...

These drugs work by inhibiting the viral reverse transcriptase enzyme, preventing the replication of the viral genetic material. Pyrimidine analogs, such as 5-fluorouracil (5-FU) and gemcitabine, are ...