Mandimycin is structurally similar to the last-line-of-defense antifungal amphotericin B, another glycosylated polyene ...

As fungi resistant to traditional treatments continue to spread around the globe, researchers from China Pharmaceutical ...

By contrast, other antifungals in this class such as amphotericin B (AmB) typically have one glycosyl group. Mandimycin is part of the family of glycosylated polyene macrolides that has provided ...

the armamentarium of antifungal agents for management of IFDs derived from just three major chemical classes: the azoles (including di- and triazoles), echinocandins and polyenes. Drugs from these ...

The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is ...