This project aims to simulate paracetamol concentrations in body districts (intestine, liver, plasma, tissue) with a deterministic model (ODE). We used the pyODE_mod file to carry out the simulation.

Abstract: Acetaminophen (APAP) overdose is the leading cause of acute liver injury in the USA and the UK. Increasingly, liver injury is caused by sustained overuse rather than a single-time overdose.