Box 1 Nicotine receptor subunits. The nicotinic acetylcholine receptor (nAChR) gene family encodes ten α subunits (α1–10), four β subunits (β1–4), and single γ, δ, and ε subunits.

The nicotinic acetylcholine receptor (AChR) is assembled on the cell surface from multiple subunits produced in the endoplasmic reticulum (ER), but how these mechanisms are controlled has been unclear ...