Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Effects of setup margin and biology tracking zone variations on dosimetric plan quality and treatment feasibility in biology-guided radiotherapy for bone metastasis.

Regeneron is integrating single-use chromatographic clarification into its commercial-scale process for manufacturing adeno-associated vectors (AAVs), which enables it to eliminate endonuclease in ...

3 In 1970, Hamilton Smith and Kent Wilcox from Johns Hopkins University discovered “endonuclease R” (later named HindII), a restriction enzyme isolated from Hemophilus influenza. 1 A year later, ...

Restriction endonucleases are enzymes that cut lengthy DNA into short pieces. Each restriction endonuclease targets different nucleotide sequences in a DNA strand and therefore cuts at different ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated naturally from an animal-to-human ...

Pairing J.T.Baker ® Cell Lysis Solution with compatible J.T.Baker ® Endonuclease — an enzyme that removes remaining impurities — can further reduce the number of steps at harvest ...

The research is published in Nature, in the paper, “Fanzor is a eukaryotic programmable RNA-guided endonuclease.” People have long wondered whether systems similar to the well-known bacterial ...